Chris O'Donnell in a comedy in 3D

MANILA, Philippines - Warner Bros. presents James Marsden (The X-Men trilogy) and Chris O’Donnell (Batman and Robin) in Cats & Dogs: The Revenge of Kitty Galore, a comedy in 3D that blends live action with state-of-the-art puppetry and computer animation.

In the movie, Kitty Galore, formerly an agent for cat spy organization MEOWS, has gone rogue and hatched a diabolical plan to not only bring her canine enemies to heel, but take down her former kitty comrades and make the world her scratching post. Faced with this unprecedented threat, cats and dogs will be forced to join forces for the first time in history in an unlikely alliance to save themselves — and their humans.

Though Marsden and O’Donnell share the screen, director Brad Peyton explains, “they rarely got a chance to interact in person, but even so, their work came together in a way that created its own chemistry and in that sense they truly were a partnership.”

That’s because Marsden was providing the voice of rookie dog agent Diggs, a German Shepherd with leadership issues, while O’Donnel plays Diggs’ compassionate human partner on the police force, Shane.

“It’s a lot of fun,” says Marsden. “This movie doesn’t take itself too seriously, although, at the same time, the characters behave as if the fate of the world was really at stake. Dogs using headsets and computer keyboards, throwing grenades; it’s all played straight and that’s what makes it so funny. The more determined they are, the crazier it is.”

While Kitty Galore grooms herself for greatness, another drama plays out on the streets of San Francisco. K-9 Officer Diggs is about to execute the latest in a series of screw-ups that will land him back in the concrete kennel.

Marsden understands how the over-eager German Shepherd sabotages his potential. “He has the best intentions in the world but not the best judgment. Wanting to be the maverick, the hero, he recklessly takes the lead in every situation, with disastrous consequences.”

“He knows he keeps messing up, but he just can’t help himself,” adds O’Donnell. “When Shane and Diggs go out on a job, sure enough, he jumps into action before he’s told. Shane knows he’s trying hard and it’s frustrating for both of them because every time they face a tough call the dog does something to make it worse — spectacularly worse.”

Opening soon in Digital 3D and regular format, Cats & Dogs: The Revenge of Kitty Galore is distributed by Warner Bros. Pictures, a Warner Bros. Entertainment Company.