Katherine Heigl leaving Grey's Anatomy?

LOS ANGELES (AP) — Grey’s Anatomy cast member James Pickens Jr. says the medical drama will say goodbye to Katherine Heigl and T.R. Knight.

Pickens, who plays Dr. Richard Webber on the ABC series, told Us Weekly magazine that Heigl and Knight are leaving.

Pickens says he wishes Heigl “nothing but the best,” the magazine reported on-line. He says his other co-star, Knight, wants to pursue other “career paths.”

Publicists for Knight and for series creator Shonda Rhimes declined comment. Requests for comment from Heigl’s publicist and ABC were not immediately returned.

Heigl plays Dr. Izzie Stevens on the series.