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                    [DatePublished] => 2007-10-14 00:00:00
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                    [AuthorID] => 1805110
                    [AuthorName] => Charles C. Chante MD
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                    [Title] => Drug found to delay type 2 diabetes
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Type 2 diabetes patients can now look forward to the potential prevention of complications of said disease after an international study found out that rosiglitazone maleate has successfully reduced the risk of monotherapy failure in people who have the disease.


Results from ADOPT (A Diabetes Outcome Progression Trial) demonstrated that initial treatment with rosiglitazone maleate reduced the risk of monotherapy failure in people with type 2 diabetes by 32 percent compared to metformin, and 63 percent compared to glyburide at five years. 


                    [DatePublished] => 2006-12-15 00:00:00
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                    [Title] => Fixed-dose combination pills recommended
                    [Summary] => Fixed-dose combination (FDC) pills are now recommended by many health experts because the combined efficacy of the component drugs are conveniently contained in one pill. Hence, better patient compliance is obtained, and the FDC pill is usually more economical.


The important criterion for recommending an FDC preparation, however, is that the component drugs must be considered rational.


Health experts explain that the components of the FDC drug must be proven to be either additive or synergistic such that the overall effect of the FDC is enhanced.


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                    [Title] => Insulin resistance needs to be addressed in diabetes
                    [Summary] => Medical experts have identified insulin resistance as a key factor which contributes to the development of complications in diabetes.


Diabetes is a chronic, progressive disease associated with high levels of glucose in the bloodstream (hyperglycemia).  Diabetes mellitus, the most common type of diabetes, is characterized by beta-cell dysfunction where the pancreas is unable to produce adequate insulin. Insulin resistance also develops, which is a condition wherein the body fails to respond to the circulating insulin effectively.  


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ROSIGLITAZONE

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                    [Title] => Drug found to delay type 2 diabetes
                    [Summary] => 

Type 2 diabetes patients can now look forward to the potential prevention of complications of said disease after an international study found out that rosiglitazone maleate has successfully reduced the risk of monotherapy failure in people who have the disease.


Results from ADOPT (A Diabetes Outcome Progression Trial) demonstrated that initial treatment with rosiglitazone maleate reduced the risk of monotherapy failure in people with type 2 diabetes by 32 percent compared to metformin, and 63 percent compared to glyburide at five years. 


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The important criterion for recommending an FDC preparation, however, is that the component drugs must be considered rational.


Health experts explain that the components of the FDC drug must be proven to be either additive or synergistic such that the overall effect of the FDC is enhanced.


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                    [ArticleID] => 232081
                    [Title] => Insulin resistance needs to be addressed in diabetes
                    [Summary] => Medical experts have identified insulin resistance as a key factor which contributes to the development of complications in diabetes.


Diabetes is a chronic, progressive disease associated with high levels of glucose in the bloodstream (hyperglycemia).  Diabetes mellitus, the most common type of diabetes, is characterized by beta-cell dysfunction where the pancreas is unable to produce adequate insulin. Insulin resistance also develops, which is a condition wherein the body fails to respond to the circulating insulin effectively.  


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abtest

Rosiglitazone has lower treatment failure rate

By YOUR DOSE OF MEDICINE | By Charles C. Chante MD | October 14, 2007 - 12:00am

Opinion

Drug found to delay type 2 diabetes

December 15, 2006 - 12:00am

Type 2 diabetes patients can now look forward to the potential prevention of complications of said disease after an international study found out that rosiglitazone maleate has successfully reduced the risk of...

Cebu News

Fixed-dose combination pills recommended

December 25, 2003 - 12:00am

Fixed-dose combination (FDC) pills are now recommended by many health experts because the combined efficacy of the component drugs are conveniently contained in one pill. Hence, better patient compliance is obtained,...

Science and Environment

Insulin resistance needs to be addressed in diabetes

December 18, 2003 - 12:00am

Medical experts have identified insulin resistance as a key factor which contributes to the development of complications in diabetes. Diabetes is a chronic, progressive disease associated with high levels of glucose...

Science and Environment