It was the second title this year for the Federation Cup veteran Santos after the Philta Open last March.
Santos and Arevalo bagged the doubles title after posting a 6-3, 5-7, 6-2 upset win over top seeds Alyssa Anne Labay and Bien Zoleta.
The mens doubles title went to the top seeds Johnny Arcilla and Michael Mora III, who scored a 7-6 (2), 6-4 decision over second seeds Alexander Lazaro and Rolando Ruel Jr.
In the mens singles division, top-seed Arcilla and second pick Joseph Victorino pulled off similar hard-earned wins to advance in the championship round.
Arcilla, eyeing his ninth straight title this year, needed an extra set to conquer fourth-ranked Ruel, 6-4, 2-6, 6-1, while 2002 PCA Open champion Victorino fought back from a first-set win to prevail over Adelo Abadia, 3-6, 7-5, 6-3.